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Molecular docking The protein structures of p53 (PDB ID: 8E7A) and HDAC7 (PDB ID: 3C0Y) were obtained from the Protein Data Bank ( Ligands and receptor proteins were preprocessed using AutoDock Tools 1.5.6, and molecular docking was performed using AutoDock Vina

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Delta Sleep-Inducing Peptide (DSIP) is a nine-amino acid regulatory neuropeptide first identified in 1977 by Marcel Monnier and colleagues at the University of Basel, isolated from the cerebral venous blood of rabbits following low-frequency hypnogenic electrical stimulation of the intralaminar thalamic nuclei

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Three-times-weekly dosing (often Monday, Wednesday, Friday) further reduces usage and extends supply to approximately 16 weeks at 2mg per dose